Amoxicillin is a broad-spectrum antibiotic which provides bactericidal activity against a wide range of common gram-positive and gram-negative pathogens. Amoxicillin has bactericidal activity against susceptible organisms similar to that of ampicillin. It acts by inhibiting the biosynthesis of bacterial cell wall mucopeptides. Most strains of the following gram-positive and gram-negative bacteria have demonstrated susceptibility to amoxicillin, nonpenicillinase-producing staphylococci, alpha- and beta-hemolytic streptococci, Streptococcus faecalis, Escherichia coli and Proteus mirabilis.
Amoxicillin does not resist destruction by penicillinase; therefore, it is not effective against penicillinase-producing bacteria, particularly resistant staphylococci. Most strains of Enterobacter and Klebsiella and all strains of Pseudomonas are resistant. Amoxicillin may be given without regard to meals because it is stable in gastric acid. It is rapidly absorbed following oral administration and diffuses readily into most body fluids and tissues. It diffuses poorly into the brain and spinal fluid except when the meninges are inflamed. Most of amoxicillin is excreted in the urine unchanged.
- Broad-spectrum antibiotic that treats a wide array of bacterial infections
- Treats ear infections, urinary tract infections, and skin infections (infected bite wounds)
- Also effective against upper respiratory, bladder, and dental infections
- Sold per capsule or per tablet
How it works
Amoxicillin works by inhibiting the formation of bacterial cell walls.
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